TABLE 2.

Caspofungin, anidulafungin, and micafungin MICs in the presence and absence of 50% human serum

C. glabrata isolateMIC (μg/ml) with no human serum/50% human seruma
CaspofunginAnidulafunginMicafungin
24 h48 h24 h48 h24 h48 h
77540.25/0.50.25/0.50.125/10.125/20.125/10.125/4
77552/28/80.5/41/40.25/40.5/4
  • a MICs were read at 24 and 48 h as the lowest concentration of drug resulting in a significant (≥50%) decrease in turbidity compared to the growth control.