TABLE 2.

BUN analysis in mouse serum after drug treatment

DrugDose (mg/kg)Mean BUNa level (mg/dl) ± SE
Amphotericin B527.4 ± 7.18
1038.6 ± 6.73
2044.1 ± 6.44
Miltefosine1029.6 ± 8.28
2034.6 ± 5.37
5082.4 ± 5.29
Chlorpromazine1036.3 ± 2.53
2038.4 ± 6.86
5057.5 ± 3.32
Control (saline)b34.1 ± 2.90
  • a The reference value of BUN in mice ranges from 15 to 40 mg/dl. Values represent the means of three experiments.

  • b The control group was treated with 100 μl of saline.