TABLE 4.

Residues involved in metal coordination

SiteResidues involved in coordination
BcIIaCphAabFez-1RoocGox
1H116, H118, H196N116, H118, H196H116, H118, H196H79, E81, H146, (D165)dH54, H56, H110, (D134)d
2D120, C221, H263D120, C221, H263D120, H121, H263D83, —, H226, (D165)dD58, H59, H173, (D134)d
  • a BBL numbering (11).

  • b Monozinc enzyme with zinc ion located in site 2.

  • c Di-iron enzyme.

  • d Bridging aspartate not present in zinc-β-lactamases.