TABLE 3.

MICs and Ki(app) values of caspofungin for C. neoformans, A. fumigatus, S. cerevisiae, and N. crassaa

OrganismKi(app) (μM)MIC (μg/ml)
C. neoformans0.17 ± 0.0216
C. neoformans (cilofungin)22 ± 5.764
A. fumigatus4.1 ± 0.50.13
S. cerevisiae6.7 ± 2.20.13
N. crassa22 ± 3.44
  • a Values were determined as described in Materials and Methods. C. neoformans was also tested against cilofungin, as indicated.