TABLE 2.

MICs of β-lactams for the A. baumannii clinical isolate and cloned blaADC-7 compared to E. coli DH10B control

AntibioticMIC (μg/ml)
A. baumannii clone 9E. coli DH10B with pBC SK (+) blaADC-7E. coli DH10B pBC SK (+)E. coli DH10B
Ampicillin1,02451244
Sulbactam4>16>16>16
Ampicillin-sulbactama4/28/44/24/2
Piperacillin1283222
Tazobactam16>32>32>32
Piperacillin-tazobactamb64/832/44/0.54/0.5
Cephalothin>4,09651242
Cefoxitin>1283244
Cefepime320.060.060.06
Ceftazidime3240.130.13
Cefotaxime12840.060.06
Ertapenem20.060.060.06
Imipenem-cilistatin0.250.060.060.06
Meropenem0.250.060.060.06
Sulopenem0.50.060.060.06
  • a Ampicillin-sulbactam is in a 2/1 ratio.

  • b Piperacillin-tazobactam is in an 8/1 ratio.