TABLE 1

In vitro antifungal susceptibility profile of 221 A. fumigatus isolates tested against 3 triazoles by the CLSI microbroth method

Antifungal drugMIC (μg/ml)aNo. of isolates with MIC (μg/ml) of:
RangeGMMIC50/MIC900.030.060.1250.250.5124816
Itraconazole0.125–10.5020.5/174411159
Voriconazole0.125–20.4860.5/1253122404
Posaconazole0.03–0.50.1560.125/0.252111375615
  • a GM, geometric mean; MIC50 and MIC90, MIC values able to inhibit 50% and 90% of all strains tested.