TABLE 1

In vitro interactions of caspofungin with fluconazole and voriconazole against Candida auris

Strain no.	CAS + FLU^b				CAS + VRC^b
	MIC (μg/ml)			FICI/INT	MIC (μg/ml)			FICI/INT
	CAS	FLU	CAS/FLU	FICI/INT	CAS	VRC	CAS/VRC	FICI/INT
VPCI 482/P/13^a	2	≥64	1/32	0.75/IND	2	2	1/0.5	0.75/IND
VPCI 1132/P/13^a	2	32	1/8	0.75/IND	2	0.5	1/0.063	0.62/IND
VPCI 1133/P/13^a	4	≥64	2/64	1/IND	4	1	2/0.25	0.75/IND
VPCI 265/P/14^a	4	32	2/32	1.5/IND	4	8	2/0.25	0.75/IND
VPCI 1510/P/14^a	0.5	32	0.5/32	2/IND	0.5	4	0.5/4	2/IND
VPCI 1514/P/14^a	1	≥64	0.5/32	0.75/IND	1	0.5	1/0.25	1.5/IND
VPCI 266/P/14^a	2	≥64	1/32	0.75/IND	2	0.5	1/0.25	1/IND
VPCI 267/P/14^a	2	32	1/8	0.75/IND	2	0.5	2/0.063	0.62/IND
VPCI 487/P/14^a	1	≥64	0.5/8	0.56/IND	1	1	0.5/0.125	0.62/IND
VPCI 518/P/14^a	0.5	≥64	0.25/8	0.56/IND	0.5	1	0.25/0.25	0.75/IND

↵a Fluconazole-resistant isolates (n = 10).
↵b CAS, caspofungin; FLU, fluconazole; VRC, voriconazole; FICI, fractional inhibitory concentration index; IND, indifference; SYN, synergy; INT, interpretation.