TABLE 3.

MICs of β-lactams for A. baumannii strains

β-LactamaMIC (μg/ml) of β-lactam for A. baumanii strainb:
FER (OXA-23)CIP 70.10 (pFER)BM4547 (pFER)CLA-1 (OXA-40)CLA-1 (ΔOXA-40)CLA-1 (ΔOXA-40) (pOXA-40)MAD (OXA-58)CIP 70.10 (pMAD)BM4547 (pMAD)CIP 70.10BM4547
AMX>256>256>256>256>256>256>256>256>2563264
TIC>256>256>256>256128>256>256>256>25648
CAZ>3244>32>32>32>322424
CTX>3216>32>32>32>32328>328>32
FEP>32>32>32>3232>32>321>321>32
CPO>32>32>32>32>32>32>328>322>32
ATM12864641281281283216161616
IPM>3216>32>322>32322320.250.5
MEM>3216>32>324>32>322320.250.5
  • a AMX, amoxicillin; TIC, ticarcillin; CAZ, ceftazidime; CTX, cefotaxime; FEP, cefepime; CPO, cefpirome; ATM, aztreonam; IPM, imipenem; MEM, meropenem.

  • b MICs of β-lactams for A. baumannii FER (OXA-23), A. baumannii CIP 70.10 and A. baumannii BM4547 harboring natural plasmid pFER, A. baumannii CLA-1 (OXA-40), A. baumannii CLA-1 (ΔOXA-40) and A. baumannii CLA-1 (ΔOXA-40) harboring recombinant plasmid pOXA-40, A. baumannii MAD (OXA-58), A. baumannii CIP 70.10 and A. baumannii BM4547 harboring natural plasmid pMAD, and A. baumannii CIP 70.10 and A. baumannii BM4547 reference strains.