TABLE 1.

MICs of β-lactams for P. aeruginosa DEJ, E. coli DH10B harboring recombinant plasmid pDEJ-1 from P. aeruginosa DEJ, E. coli DH10B harboring recombinant plasmid pC1, and the E. coli DH10B reference strain

β-Lactam(s)aMIC (μg/ml) for:
P. aeruginosa DEJE. coli DH10B (pDEJ-1) (GES-9)E. coli DH10B (pC1) (GES-1)bE. coli DH10B
Amoxicillin>512>512>5122
Amoxicillin + CLA>512128>1282
Ticarcillin>512>512>5121
Ticarcillin + CLA512128641
Piperacillin1664641
Piperacillin + TZB16881
Cephalothin>5122562564
Cefuroxime>5125122562
Cefoxitin>512482
Ceftazidime>5125121280.06
Cefotaxime>5123240.06
Cefepime51210.50.06
Moxalactam>5120.120.120.06
Aztreonam5121610.12
Imipenem0.250.250.250.12
  • a CLA, clavulanic acid at a fixed concentration of 2 μg/ml. TZB, tazobactam at a fixed concentration of 4 μg/ml.

  • b Data in this column are from reference 23.