TABLE 2.

dfrA12-orfF-aadA2 cassette arrays

GenBank accession no.Sequence difference(s) in cassetteaOrganismReference or source
dfrA12orfFaadA2
Z21672 b c Escherichia coli 4
AF284063 d Serratia marcescens
AB154407 Escherichia coli
AB191048 Staphylococcus aureus
AF550415 Citrobacter freundii
AY748453 Klebsiella pneumoniae
AY852272 eMixed cultureThis work
AB191047 T178C Pseudomonas aeruginosa
AF175203 AAAA528-31AAAfGG302-303GGGf Citrobacter freundii
AY522923 G568A Aeromonas hydrophila
AF188331 GGG101-103GGgG568A Shigella flexneri
AB196348 G300A G360AG302TfA601G Enterococcus faecalis
AY115474 C567GfC50G G75A T133C C140G T248C T267GfA601GUncultured 15
AY139605 C567GfC50G G75A T133C C140G T248C T267GfA601GUncultured 15
AY551331 T115C C179TA732G Salmonella enterica serovar Choleraesuis 6
AF335108 T216Ch CCG826-828Δf Escherichia coli 8
AF180731 GC209-210CGA34G G642T C826Δf G830Δf Klebsiella pneumoniae
  • a Unless indicated otherwise, these changes are seen only in GenBank entries included in this table.

  • b Standard sequence for the dfrA12 and orfF cassettes.

  • c Sequence is only available to position 125 of the aadA2 cassette.

  • d Standard sequence for the complete dfrA12-orfF-aadA2 array.

  • e The aadA8b hybrid cassette is identical to the aadA2 cassette in AF284063 to position 602 and to the standard aadA1 cassette in X12870 from positions 647 to 856.

  • f In the 59-base element.

  • g This change disrupts the dfrA12 reading frame, and there are likely errors elsewhere in this sequence (10).

  • h Found in the prototype aadA2 sequence in X68227.