TABLE 1.

Characteristics and phylogenetic background of 56 extended-spectrum beta-lactamase-producing Escherichia coli isolates from community and hospital sites in the Calgary Health Region

Type of ESBL produced by organism (no. of organisms)PFGE patternaNo. of isolates (% of total)b
Isolated from urineRepeat infectionsResistant to ciprofloxacinPhylogenetic group
ADB1B2
CTX-M-14 (11)CTXM14A11 (100)4 (36)10 (91)011 (100)00
CTX-M-14 (8)CTXM14AR5 (63)4 (50)8 (100)08 (100)00
CTX-M-14 (8)CTXM14NR5 (63)1 (12)6 (75)07 (88)01 (12)
CTX-M-15 (9)NRB6 (67)2 (22)9 (100)2 (22)1 (11)06 (67)
CTX-M-3 (1)NRC1101000
TEM (8)NRD7 (88)1 (12)3 (38)2 (25)2 (25)1 (12)3 (38)
SHV (10)NRE8 (80)02 (20)1 (10)6 (60)1 (10)2 (20)
VEB-1 (1)NRF1011000
  • a The CTXM14A isolates formed a cluster with >80% similar PFGE profiles. The CTXM14AR isolates exhibited >60% similarity of profiles to CTXM14A and each other, while the CTXM14NR isolates were more distantly related to these two groups. The remaining strains (PFGE groups NRB, NRC, NRD, NRE, and NRF) were not clonally related, i.e., exhibited <80% similar PFGE profiles.

  • b Percentage not shown for groups containing a single isolate.