TABLE 1.

MICs of the Acinetobacter isolates included in this study

Antibiotic(s)MIC (μg/ml)
JC10/01bEG-1cEG-1revdJC10/01 (pAT-RA-34s)eJC10/01 (pAT-RA-34r)eJC10/01 (pAT-RA-c)e
Amoxicillin>256>256>256>256>256>256
Amoxicillin-clavulanatea>25648>2563248>256
Piperacillin>256>256>256>256>256>256
Cefalothin>256>256>256>256>256>256
Cefuroxime>256>256>256>256>256>256
Cefoxitin>256>256>256>256>256>256
Cefotaxime>256>256>256256256>256
Ceftazidime128481283248128
Cefepime481248121232
Aztreonam256482564848128
Imipenem324>322416
Meropenem>3212>32812>32
Tobramycin444444
Amikacin128128128128128128
Ciprofloxacin>32>32>32>32>32>32
Tetracycline>256>256>256>256>256>256
  • a Clavulanic acid was used at a concentration of 4 μg/ml.

  • b JC10/01, A. baumannii epidemic strain from the index case of the outbreak.

  • c EG-1, A. baumannii revertant from the JC10/01 strain.

  • d EG-1rev, A. baumannii revertant from the EG-1 strain.

  • e JC10/01 strain was transformed with the indicated plasmids. MICs were determined in the presence of 50 μg/ml of rifampin. Identical MICs were obtained with three different transformants in each case.