TABLE 2.

KPC-2 kinetic parametersa

DrugKm (μM)kcat(s−1)kcat/Km ratio (μM−1 s−1)
Piperacillin16 ± 217 ± 61.1 ± 0.2
NCF5 ± 130 ± 16.4 ± 0.2
Cefotaxime120 ± 1478 ± 50.6 ± 0.1
Imipenem19 ± 119 ± 11.0 ± 0.1
  • a Values are means ± standard deviations.