TABLE 2.

Univariate analysis for association with microbiological response

VariableMicrobiological failure (n = 24)Microbiological success (n = 32)P value
Mean (SD) age (yr)59.4 (22.4)62.0 (17.9)0.624
Mean (SD) APACHE II score14.6 (6.2)13.2 (7.6)0.443
Mean (SD) CLCR (ml/min)110 (57)91.3 (50.5)0.199
No. (%) of patients with the following comorbidities:
    Diabetes9 (37.5)11 (34.4)0.968
    Cardiovascular disease12 (50)10 (31.3)0.252
    Chronic renal failure4 (16.7)7 (21.9)0.741
    Immunosuppression0 (0)4 (12.5)0.127
No. (%) of patients with infection at the following site:
    Respiratory20 (83.3)17 (53.1)0.038
    Bacteremia2 (8.3)3 (9.4)1.000
    Skin and skin structure2 (8.3)12 (37.5)0.029
No. (%) of patients receiving combination therapy13 (54.2)8 (25.0)0.051