TABLE 3.

Target values of colistin fAUC/MIC for stasis and 1-, 2-, and 3-log10 kill against all three P. aeruginosa strains in the thigh and lung infection models

Model and kill effectTarget value of colistin fAUC/MIC for strain:
ATCC 27853PAO119056
Thigh infection
    Static effect17.314.48.34
    1-log10 kill22.722.815.6
    2-log10 kill31.236.127.6
    3-log10 kill55.166.753.3
Lung infection
    Static effect6.435.424.07
    1-log10 kill15.616.712.2
    2-log10 kill37.945.936.9
    3-log10 kill105135141