TABLE 1.

IC50 values for the strains in this study

StrainIC50 (μM) of compounda:
APMBenfluralinButralinDinitramineEthalfluralinFluchloralinGB-II-5IsopropalinNitralinOryzalinPendimethalinProfluralinTrifluralin
RH1.0 ± 0.11.5 ± 0.11.8 ± 0.2 0.045 ± 0.008 0.26 ± 0.010.33 ± 0.096.7 ± 0.70.88 ± 0.080.50 ± 0.02 0.25 ± 0.02 0.26 ± 0.030.61 ± 0.100.52 ± 0.06
V4L 2.1 ± 0.3 18.8 ± 0.832.1 ± 0.9 3.4 ± 0.513.5 ± 2.08.0 ± 0.226.2 ± 1.37.0 ± 1.019.2 ± 2.614.7 ± 1.8 3.2 ± 0.68.2 ± 0.513.8 ± 1.9
S6I3.3 ± 0.47.4 ± 0.54.5 ± 0.1 0.42 ± 0.06 2.5 ± 0.11.9 ± 0.312.4 ± 1.02.2 ± 0.12.1 ± 0.21.5 ± 0.0 0.75 ± 0.162.6 ± 0.292.8 ± 0.6
F24H10.0 ± 0.715.7 ± 0.624.2 ± 1.6 0.37 ± 0.03 2.1 ± 0.33.2 ± 0.217.2 ± 1.63.5 ± 0.43.7 ± 0.0 1.26 ± 0.13.2 ± 0.14.3 ± 0.14.2 ± 0.5
H28Q5.1 ± 0.715.2 ± 1.010.2 ± 0.9 0.51 ± 0.02 4.2 ± 0.5 1.6 ± 0.412.4 ± 1.53.4 ± 0.21.8 ± 0.1 1.4 ± 0.22.5 ± 0.12.8 ± 0.245.3 ± 0.4
L136F28.5 ± 1.327.7 ± 1.432.0 ± 1.1 12.5 ± 1.024.0 ± 3.222.2 ± 1.0 9.7 ± 1.6 15.0 ± 1.031.3 ± 2.127.7 ± 0.313.2 ± 2.721.2 ± 1.427.0 ± 1.0
I235L3.9 ± 0.54.6 ± 1.09.1 ± 1.7 0.32 ± 0.04 1.4 ± 0.3 1.0 ± 0.37.7 ± 1.12.2 ± 0.12.1 ± 0.51.6 ± 0.1 1.0 ± 0.11.5 ± 0.21.9 ± 0.1
I235T7.1 ± 1.09.3 ± 1.27.4 ± 0.2 0.32 ± 0.06 1.7 ± 0.22.1 ± 0.116.9 ± 0.34.3 ± 0.24.9 ± 0.45.5 ± 0.2 0.71 ± 0.023.9 ± 0.35.1 ± 0.6
I235V1.5 ± 0.13.7 ± 0.43.8 ± 0.4 0.089 ± 0.005 0.65 ± 0.090.77 ± 0.084.7 ± 1.22.2 ± 0.21.6 ± 0.12.3 ± 0.1 0.34 ± 0.011.5 ± 0.31.8 ± 0.6
T239I28.5 ± 0.822.9 ± 1.328.7 ± 3.526.6 ± 0.428.7 ± 2.520.5 ± 2.317.1 ± 0.4 15.0 ± 1.630.3 ± 1.225.3 ± 2.3 12.2 ± 0.8 22.1 ± 0.423.4 ± 0.7
R243C5.9 ± 0.512.0 ± 0.112.8 ± 1.4 0.33 ± 0.03 1.6 ± 0.22.2 ± 0.117.0 ± 0.74.0 ± 0.44.3 ± 0.22.2 ± 0.0 1.1 ± 0.13.2 ± 0.34.1 ± 0.4
R243S19.1 ± 1.121.7 ± 0.825.1 ± 1.118.4 ± 2.719.5 ± 1.617.7 ± 0.9 13.3 ± 1.4 13.5 ± 1.423.9 ± 1.216.0 ± 0.5 9.7 ± 0.920.4 ± 0.923.3 ± 1.7
  • a Results for the most effective compounds are shown in boldface. Results for the second most effective compounds are shown in italic.