TABLE 2.

ORFs in and around SCCmecC10682

Genetic regionORF or key structural componentaPosition (bp)Size (bp)Protein size (aa)b% IdentityHomolog(s) (strain[s])Informationc
ChromosomeorfX1-151151NA100SARCOL0025 (COL)Conserved hypothetical protein (partial cds)
Repeat regionDRSCC-R137-14812NADirect repeat at right extremity of SCCmec
DyadR-R240-25415NA100; 100(COL); (RP62A)Dyad repeat at right extremity of SCCmec
J3CA001329-16241,296431100SERP2528 (RP62A)Conserved hypothetical protein
CA0022039-227824079100SERP2527 (RP62A)Conserved hypothetical protein
mec gene complexIR-R*2250-226617NA100(RP62A)Right inverted complementary repeat of IS431 element
tnp*2310-2984675224100SERP2526 (RP62A)Transposase for IS431 element
IR-L*3025-304117NA100(RP62A)Left inverted complementary repeat of IS431 element
CA0043242-340916855100SERP2525 (RP62A)Truncated probable HMG-CoA synthase
CA0053507-373723176100SERP2524 (RP62A)Conserved hypothetical protein
CA0064246-4989744247100SERP2523 (RP62A)Glycerophosphoryldiester phosphodiesterase homologue
CA0075086-5514429142100SERP2522 (RP62A)MaoC domain protein dehydratase
mecA5560-75662,007668100SERP2521 (RP62A)Penicillin binding protein 2′
mecR17666-94231,758585100SERP2520 (RP62A)Methicillin resistance protein
mecI9423-9794372123100SERP2519 (RP62A)Methicillin resistance regulatory protein
J2CA0119895-1010721370100SERP2518 (RP62A)Conserved hypothetical protein
xylR10302-114111,110369100SERP2517 (RP62A)Xylose repressor homologue
CA01311525-1178526186100SERP2516 (RP62A)Conserved hypothetical protein
CA01411921-1278186128699SERP2516 (RP62A)Conserved hypothetical protein
CA01512892-139561,065354100SERP2515 (RP62A)Rhodanese-like domain protein
CA01614092-1435226186100SERP2514 (RP62A)Conserved hypothetical protein
CA01714352-14996645214100SERP2513 (RP62A)Conserved hypothetical protein
CA018**15335-15946612203100SERP2512 (RP62A)Methyltransferase type 12
CA019**16356-1655620166100SERP2511 (RP62A)Peptide L
ermA**16531-17262732243100SERP2510 (RP62A)rRNA adenine N-6-methyltransferase
aad(9)**17388-18170783260100SERP2509 (RP62A)Streptomycin 3′-adenyltransferase
tnpC**18321-18698378125100SERP2508 (RP62A)Transposase C
tnpB**18705-205971893630100SERP2507 (RP62A)Transposase B
tnpA**20594-216791,086361100SERP2506 (RP62A)Transposase A
CA02521798-22115318105100SERP2505 (RP62A)Truncated radC DNA repair protein
CA02622136-2264250716896; 87SERP2504 (RP62A); SE0052 (ATCC 12228)Hypothetical protein
CA02722658-2296931210396; 95SERP2503 (RP62A); SE0053 (ATCC 12228)Hypothetical protein
CA02822971-23063933097; 84SERP2502 (RP62A); SE0054 (ATCC 12228)Conserved hypothetical protein
CA02923056-2340635111690; 98SERP2501 (RP62A); SE0055 (ATCC 12228)Conserved hypothetical protein
ccr gene complexccrB423907-255351,62954299SE0056 (ATCC 12228)Cassette chromosome recombinase B4
ccrA425532-268931,362453100SE0057 (ATCC 12228)Cassette chromosome recombinase A4
J1CA03227080-27661582193100SE0058 (ATCC 12228)Putative membrane protein
ccrA27937-2805612039100SE0059 (ATCC 12228)Cassette chromosome recombinase A
CA03428168-28527360119100SE0060 (ATCC 12228)Hypothetical protein
CA03529163-292619932100SE0061 (ATCC 12228)Hypothetical protein
copA29381-313151,93564499SE0062 (ATCC 12228)Copper-transporting ATPase CopA
Repeat regionDyadR-L32040-3205415NADyad repeat at left extremity of SCCmec
DRSCC-L32310-3232112NA100; 93(HDE288); (COL)Direct repeat at left extremity of SCCmec
ChromosomeCA03732624-327169330100SACOL0057 (COL)Conserved hypothetical protein
CA03832863-33371509NA100SACOL0058 (COL)Conserved hypothetical protein (partial cds)
  • a *, IS431; **, Tn554.

  • b NA, not applicable.

  • c cds, coding region; HMG-CoA, 3-hydroxy-3-methylglutaryl-coenzyme A.