TABLE 1

Log10 change in viable counts compared to those at 0 h for AH298-GFP in the first set of static concentration time-kill studies at an initial inoculum of ∼107.6 CFU/mla

TABLE 1
  • a Cells shaded in dark gray represent >2 log10 more bacterial killing than the most active monotherapy (i.e., meeting the empirical definition of synergy), and cells shaded in light gray represent 1.0 to 2.0 log10 more killing than the most active monotherapy. IPM, imipenem; TOB, tobramycin; MEM, meropenem; DOR, doripenem.