TABLE 1.

In vitro susceptibilities of Plasmodium falciparum lines to artelinic acid

Parasite lineMean IC (nM) ± SDa
50%90%
W24.73 ± 0.197.45 ± 0.40
W2AL5023.30 ± 3.9551.31 ± 1.31
W2AL8022.75 ± 5.3756.80 ± 5.44
D69.81 ± 1.4121.83 ± 3.04
D6AL5034.00 ± 3.1481.26 ± 8.67
D6AL8023.64 ± 3.7175.89 ± 2.60
TM91C23511.08 ± 1.6822.99 ± 2.60
TM91C235AL5033.72 ± 1.6453.51 ± 1.12
TM91C235AL8024.55 ± 4.1375.89 ± 6.8