TABLE 2.

Systemic adverse events judged by the investigator as related to the study drug in part 1 of the studya

EventNo. of occurrences in cohort
Total placebo (n = 10)250 mg (n = 6)500 mg (n = 6)1,000 mg (n = 6)1,500 mg (n = 6)2,000 mg (n = 6)
Abdominal pain1
Nausea1
Headache111
Paresthesia1
Somnolence1
Vulvo-vaginal pruritus1
  • a Single doses of CXA-101 or placebo (6 CXA-101, 2 placebo per cohort).