TABLE 4.

Selected genes from the microarray analysis of genes expressed differently in the presence of 4 μg/ml indolicidin in the parR mutant compared to the WTa

GeneIDGene nameFold changebP valueDescription
PA0282cysT−2.30.03Sulfate transport protein CysT
PA0517nirC2.70.04Probable c-type cytochrome precursor
PA0523norC6.00.01Nitric oxide reductase subunit C
PA0524norB10.70.009Nitric oxide reductase subunit B
PA1559−4.2<0.001Hypothetical protein
PA1560−2.9<0.001Hypothetical protein
PA1797−3.3<0.001Hypothetical protein
PA3392nosZ2.10.04Nitrous oxide reductase precurser
PA3396nosL2.00.04NosL protein
PA3446−5.80.0007Hypothetical protein
PA3552arnB−1.60.0009Hypothetical protein
PA3553arnC−2.0<0.001Probable glycosyltransferase
PA3554arnA−2.5<0.001Hypothetical protein
PA3555arnD−2.9<0.001Hypothetical protein
PA3556arnT−2.10.003Inner membrane l-Ara4N transferase ArnT
PA3559pmrE−3.3<0.001Probable nucleotide sugar dehydrogenase
PA39202.30.0059Membrane proteins/transport of small molecules
PA4661pagL−2.5<0.001Lipid A 3-O-deacylase
PA4773−5.1<0.001Hypothetical protein
PA4774−7.4<0.001Hypothetical protein
PA4775−3.3<0.001Hypothetical protein
PA4776pmrA−2.10.003Two-component system response regulator
PA4777pmrB−1.70.002Two-component system signal sensor kinase
PA4782−6.7<0.001Hypothetical protein
  • a The full list of dysregulated genes is given in Table S1 in the supplemental material.

  • b Fold change in gene expression in the presence of 4 μg/ml indolicidin in the parR mutant compared to gene expression in the presence of 4 μg/ml indolicidin in the WT.