TABLE 1.

IC50s of quinine and pfnhe polymorphisms in P. falciparum

IsolateIC50 (nM)Codon polymorphismsMicrosatellite polymorphisms
8949501437No. of SDNN repeatsmsR1ms3580ms4760
3D727.1AATGTGTAT4AbsentNIHms4760-2
AK127569.5AATGGGTAT4TCDNNMPNNNMSNNNNIHms4760-1
AK182549.2AATGGGTTT2TCDNNMPNNNMSNNNNIHms4760-1
AK227495.3AATGGGTAT4TCDNNMPNNNMSNNNNIHms4760-1
CDA-1553333.3AATGGGTTT4TCDNNMPNNNMSNNNNIHms4760-1
AK150 D-0296.6AATGGGTAT3AbsentNIHms4760-1
AK249270.4AATGTGTAT3AbsentNIHms4760-1
AK121270.2AATGGGTAT4TCDNNMPNNNMSNNNNIHms4760-21
AK158234.0AATGGGTAT2TCDNNMPNNNMSNNNNIHms4760-1
AK167227.0AATGGGTAT4TCDNNMPNNNMSNNNNIHms4760-1
AK222210.5AATGGGTAT2TCDNNMPNNNMSNNNNIHms4760-1
AK152 D-56207.7AAAGTGTAT2AbsentNIHms4760-6
AK062181.5AATGTGTAT4TCDNNMPNNNMSNNNNIHms4760-1
AK144145.8AATGTGTTT4AbsentNIHms4760-23
AK018141.1AATGGGTTT2AbsentNIHms4760-20
AK150 D-4291.6AATGGGTAT2AbsentNIHms4760-1
906780.1AATGTGTAT4TCDNNMPNNNMSNNNNIHms4760-3
888578.2AATGGGTAT3AbsentNIHms4760-22
AK18373.9AATGGGTTT4TCDNNMPNNNMSNNNAbsentms4760-20
681673.3AATGGGTAT1TCDNNMPNNNMSNNNNIHms4760-18
896655.8AATGTGTAT4TCDNNMPNNNMSNNNAbsentms4760-1
AK033 D-4954.1AATGGGTAT3TCDNNMPNNNMSNNNNIHms4760-7
AK022D-042.4AATGGGTAT4TCDNNMPNNNMSNNNNIHms4760-22
907041.5AATGGGTAT4TCDNNMPNNNMSNNNNIHms4760-22
897735.9AATGGGTTT3AbsentNIHms4760-7
AK033 D-032.8AATGGGTAT4AbsentNIHms4760-1
896830.6AAAGGGTAT4AbsentNIHms4760-2
894827.8AAAGGGTAT4AbsentNIHms4760-7
AK022 D-2822.0AATGGGTAT4TCDNNMPNNNMSNNNNIHms4760-1
897320.0AATGGGTAT4TCDNNMPNNNMSNNNNIHms4760-7