Statistic | Random parameters | Fixed parameters | ||||||||
---|---|---|---|---|---|---|---|---|---|---|

CL_{23} | CL_{24} | CL_{34} | V_{2} | V_{3} | V_{4} | CL_{10} | K_{12} | K_{21} | V_{1} | |

Mean | 0.279 | 0.00967 | 0.362 | 5.407 | 1.607 | 12.024 | 1.309 | 3.068 | 6.795 | 17.617 |

Median | 0.0903 | 0.0118 | 0.0143 | 3.519 | 0.851 | 15.361 | ||||

SD | 0.772 | 0.0236 | 0.708 | 4.992 | 1.455 | 5.712 |

↵

*a*Subscript numeral correspond to compartments as follows: 1, central (plasma) compartment; 2, peripheral compartment; 3, AC compartment; 4, ELF compartment.*K*_{12}and*K*_{21}(in h^{−1}) are transfer rate constants between the central and the peripheral compartments. CL_{10}(in liters/h) is the elimination clearance from the central compartment; CL_{23}, CL_{24}, CL_{34}(in liters/h) are the intercompartmental clearances.*V*_{1},*V*_{2},*V*_{3}, and*V*_{4}(in liters) are the volumes of distribution in the indicated compartment.