TABLE 1.

List of strains and their antimicrobial susceptibility profiles to DAP and vancomycin

StrainLength of serial passage (days)Mutation(s)MIC (μg/ml) of:
DAPVANa
Parental
    CB1118 (MW2)12
Passage set
    CB22011Acetate CoA ligaseb1.53
    CB22025Acetate CoA ligase MprFT345I33
    CB220314Acetate CoA ligase MprFT345I RpoBI953S64
    CB220520Acetate CoA ligase MprFT345I RpoBI953S YycGS221P124
  • a VAN, vancomycin.

  • b Noncoding region. CoA, coenzyme A.