TABLE 1

Background characteristics of subjects treated for gonococcal urethritis with a single 2-g dose of AZM-SRc

CharacteristicValue(s) for subjects who achieved microbiological:P valueb
Cure (n = 30)Failure (n = 6)
Mean ± SDRangeMean ± SDRange
Age (yr)31.5 ± 8.220–5430.7 ± 9.424–450.83
Wt (kg)68.5 ± 11.355–10067.3 ± 13.847–800.82
WBC count (no./μl)6,677 ± 2,4573,800–16,5007,083 ± 1,9384,700–8,8000.71
AST concn (IU/liter)19.8 ± 10.712–7220.3 ± 6.912–310.91
ALT concn (IU/liter)24.0 ± 28.59–16821.5 ± 10.78–390.84
ALP concn (U/liter)234.0 ± 65.5159–462246.8 ± 58.8139–3150.66
T-bil concn (mg/dl)0.63 ± 0.230.1–1.10.67 ± 0.250.3–0.90.70
Cr concn (mg/dl)0.83 ± 0.090.65–0.980.86 ± 0.100.71–0.940.38
CLCRa (ml/min)125.6 ± 22.795.1–187.1117.8 ± 17.999.0–143.20.44
  • a CLCR was calculated using the Cockcroft-Gault equation.

  • b Determined by Student's t test.

  • c The data are for 36 subjects. WBC, white blood cell; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; T-bil, total bilirubin; Cr, creatinine; CLCR, creatinine clearance.