TABLE 3.

Summary of pfnhe-1 ms4760 haplotypes, His/Asp ratios, DNNND copy numbers, and in vitro QN responses (IC50) of 60 field P. falciparum isolates

His/Asp ratioams4760 haplotype(s)No. of isolatesNo. of DNNND copiesIC50(nM) (mean ± SD)
5:85, 3434462 ± 123
5:67313661 ± 374
6:61413767
7:6923837 ± 372
5:46102580 ± 254
7:41, 1892312 ± 115
5:23511260
6:2331223 ± 106
  • a ms4760 haplotypes found among the China-Myanmar border parasite population are grouped here by His/Asp ratios, which are arranged from low to high values.