TABLE 7.

Multivariate analysis comparing patients carrying fluoroquinolone-resistant and -sensitive strains in each commensal flora

Organism and parameterFQ-SaFQ-RbORcCIdP value
E. coli
    No. of patients positive31842
    Carriage of multiresistant bacteria (no. of patients [%])29 (9.1)17 (40.5)6.78(3.28-13.99)<0.0001
α-Hemolytic streptococci
    No. of patients positive386151
    Period of antibiotic exposure (no. of patients [%])
        0 days193 (50.1)93 (61.6)10.0122
        1-7 days120 (31.2)28 (18.5)0.48(0.3-0.78)
        >8 days72 (18.7)30 (19.9)0.87(0.53-1.42)
CNS
    No. of patients positive333168
    Avg age (yr)63.269.91.18*(1.18-1.31)0.0021
    Not coming from home (no. of patients [%])57 (17.1%)61 (36.3)2.18(1.38-3.43)0.0008
    Period of antibiotic exposure (no. of patients [%])
        0 days195 (58.6)68 (40.7)1<0.0001
        1-7 days94 (28.2)48 (28.7)1.16(0.73-1.85)
        >8 days44 (13.2)51 (30.5)3.09(1.85-5.14)
S. aureus
    No. of patients positive7422
    Avg age (yr)67.276.41.37(1.1-1.87)0.049
    Previous fluoroquinolone treatment (no. of patients [%])7 (9.5)8 (36.4)6.26(1.84-21.36)0.0034
  • a Fluoroquinolone-sensitive.

  • b Fluoroquinolone-resistant.

  • c Odds ratio. *, per 10 years.

  • d Confidence interval.