TABLE 2.

Distribution of MICs for three echinocandins for 490 C. glabrata isolates

AntifungalNo. of strains at MIC (μg/ml) (no. of isolates with FKS mutation)a
≤0.0080.0150.030.060.1250.250.51248≥16
Anidulafungin112164246 (1)521 (1)3 (3)2 (2)7 (7)2 (2)
Caspofungin417624055 (1)2 (2)2 (2)2 (2)2 (2)1 (1)1 (1)5 (5)
Micafungin413389141 (1)3 (3)2 (2)1 (1)4 (4)5 (5)
  • a Not all isolates with MICs of <0.125 μg/ml were screened for FKS mutations; any appearing at those values relate to a higher value for one of the other echinocandins.