TABLE 3.

Incidence of acquisition for 1,000 antibiotic-days by antibiotic class, patient risk factor, and duration of therapy for the overall target ARB (i.e., MRSA, VRE, and CR-PA) and specific for MRSA

Antibiotic class and risk factoraARB incidence/1,000 days of antibioticMRSA incidence overall
OverallBy duration of therapy:
5 days10 days15 days
Carbapenems13.818.313.27.67.9
    Dialysis29.4
    Diabetes28.6
    ICU22.8
    Cirrhosis20.4
Broad-spectrum cephalosporins5.85.13.513.52.4
    Chronic renal failure27.3
    Cancer15.8
    HIV infection10.9
    Cirrhosis10.6
    Age of >70 yrs8.1
Quinolones5.96.65.217.23.1
    Age of >70 yrs8.3
Glycopeptides9.211.38.021.73.2
    HIV19.5
    Cirrhosis15.1
Macrolides5.87.210.96.38.2
    Chronic renal failure22.7
    Cancer16.8
Piperacillin-tazobactam6.5113.13.5
    Age of >70 yrs16.2
  • a Only relevant risk factors are reported.