TABLE 1.

Susceptibilities of the K. pneumoniae isolates and of the E. coli transconjugants obtained in the study

Isolate(s)MICa (μg/ml) of:
AMPAMCPIPTZPCAZCTXFEPIPMMEMAMKGENCIPTETTGCCST
Clinical isolates>256>256>256>256>256128>322-33-412-161-1.5>3232-4830.38-0.75
KPC-2/TEM-1-producing transconjugant 2641/08>256249648321.530.751.50.250.02320.380.25
SHV-12-producing transconjugants>2564-632-481-1.5161.5-20.50.250.0471-1.50.19-0.250.0161.5-20.38-0.50.19-0.25
E. coli A15341.510.250.0470.0470.250.03210.190.02320.380.25
  • a Abbreviations: AMK, amikacin; AMC, amoxicillin-clavulanic acid; AMP, ampicillin; CAZ, ceftazidime; CIP, ciprofloxacin; CST, colistin; CTX, cefotaxime; FEP, cefepime; GEN, gentamicin; IPM, imipenem; MEM, meropenem; PIP, piperacillin; TET, tetracycline; TGC, tigecycline; TZP, piperacillin-tazobactam. In the case of β-lactam antibiotics, the MICs shown are the values indicated by zones of confluent growth around Etest strips; the clinical isolates and the E. coli transformants with KPC-2 produced scattered colonies inside the growth inhibition zones (15).