TABLE 2.

SCCmec elements identified in MRSAa

SCCmec typebReported namecMajor characteristics of J regionsdRepresentative strain(s)Reference(s) and/or accession no.e
I (1B)IJ1, subtype 1-specific ORFs (pls); J3, dcsNCTC10442, COL9, 18
I.2J1, subtype 2-specific ORFs; J3, dcs and pUB110PL7218
II (2A)IIJ1, subtype 1-specific ORFs (kdp); J2, subtype 1-specific ORFs and Tn554; J3, dcs and pUB110N31518
IIbJ1, subtype 2-specific ORFs; J2, subtype 1-specific ORFs and Tn554; J3, dcsJCSC30637
IIBJ1, subtype 3-specific ORFs; J2, subtype 1-specific ORFs; J3, dcs and pUB110AR05/0.134520
IIEJ1, subtype 3-specific ORFs; J2, short J2 region the same as subtype 1 and Tn554; J3, dcs and pUB110AR13.1/3330.220
II.4.1.1J1, subtype 4-specific ORFs; J2, subtype 1-specific ORFs and Tn554; J3, dcs and pUB110RN717013
III (3A)IIIJ1, subtype 1-specific ORFs; J2, subtype 1-specific ORFs and ΨTn554; J3, subtype 1-specific ORFs and pT18185/2082, ANS469, 18
IIIAJ1, subtype 1-specific ORFs; J2, subtype 1-specific ORFs and ΨTn554; J3, subtype 1-specific ORFs, pT181, and SCCHg carrying ccrCHU2518
IV (2B)IVaJ1, subtype 1-specific ORFs; J3, dcsCA05, MW215
IVbJ1, subtype 2-specific ORFs; J3, dcs8/6-3P15
IVcJ1, subtype 3-specific ORFs; J3, dcs and Tn400181/10816
IVcJ1, subtype 3-specific ORFs; J3, dcs2314AY271717
IVAJ1, subtype 3-specific ORFs; J3, dcs and pUB110cm11EU437549
IVEJ1, subtype 3-specific ORFs; J3, subtype 2-specific ORFsAR43/3330.120
IVdJ1, subtype 4-specific ORFs; J3, dcsJCSC446916
IVgJ1, subtype 5-specific ORFs; J3, dcsM03-6814
IVhJ1, subtype 6-specific ORFs; J3, dcsEMRSA-1517
IViJ1, subtype 7-specific ORFs; J3, dcsJCSC66682
IVjJ1, subtype 8-specific ORFs; J3, dcsJCSC66702
IV (2B&5)IV variantJ1, subtype 3-specific ORFs; J3, SCC carrying ccrCZH476
V (5C2)VJ1, subtype 1-specific ORFs; J2, subtype 1-specific ORFs; J3, subtype 1-specific ORFsWIS(WBG8318)10
V (5C2&5)VT, VIIJ1, subtype 2-specific ORFs; J2, sutype 2-specific ORFs; J3, SCC carrying ccrCTSGH17, PM13, 22
VI (4B)VIJ1, subtype 1-specific ORFs; J3, dcsHDE28819
VII (5C1)5C1J1, subtype 1-specific ORFs; J2, subtype 1-specific ORFs; J3, subtype 1-specific ORFsJCSC60821
VIII (4A)VIIIJ1, subtype 1-specific ORFs; J2, subtype 1-specific ORFs; J3, subtype 1-specific ORFsC10682, BK2078123; FJ670542
  • a SCCmec elements that satisfy the following criteria are listed as follows: entire regions of SCCmec elements have been sequenced, or the essential parts of the mec gene complex and the ccr gene complex have been fully sequenced.

  • b The first categories for classifying SCCmec elements. The combinations of the ccr gene complex and the mec gene complex carried by the elements are indicated in parentheses.

  • c The names reported in original literature are listed. Assigned numbers or names that specify these elements would be given by IWG-SCC and would be seen at the website (http://www.SCCmec.org [under construction]).

  • d Key loci are indicated in parentheses. pls, plasmin-sensitive surface protein; dcs, downstream constant segment; kdp, potassium-dependent ATPase operon.

  • e GenBank/EMBL/DDBJ accession numbers are indicated in cases of direct submission.