TABLE 2.

SCCmec elements identified in MRSAa

SCCmec typebReported namecMajor characteristics of J regionsdRepresentative strain(s)Reference(s) and/or accession no.e
I (1B)IJ1, subtype 1-specific ORFs (pls); J3, dcsNCTC10442, COL 9, 18
I.2J1, subtype 2-specific ORFs; J3, dcs and pUB110PL72 18
II (2A)IIJ1, subtype 1-specific ORFs (kdp); J2, subtype 1-specific ORFs and Tn554; J3, dcs and pUB110N315 18
IIbJ1, subtype 2-specific ORFs; J2, subtype 1-specific ORFs and Tn554; J3, dcsJCSC3063 7
IIBJ1, subtype 3-specific ORFs; J2, subtype 1-specific ORFs; J3, dcs and pUB110AR05/0.1345 20
IIEJ1, subtype 3-specific ORFs; J2, short J2 region the same as subtype 1 and Tn554; J3, dcs and pUB110AR13.1/3330.2 20
II.4.1.1J1, subtype 4-specific ORFs; J2, subtype 1-specific ORFs and Tn554; J3, dcs and pUB110RN7170 13
III (3A)IIIJ1, subtype 1-specific ORFs; J2, subtype 1-specific ORFs and ΨTn554; J3, subtype 1-specific ORFs and pT18185/2082, ANS46 9, 18
IIIAJ1, subtype 1-specific ORFs; J2, subtype 1-specific ORFs and ΨTn554; J3, subtype 1-specific ORFs, pT181, and SCCHg carrying ccrCHU25 18
IV (2B)IVaJ1, subtype 1-specific ORFs; J3, dcsCA05, MW2 15
IVbJ1, subtype 2-specific ORFs; J3, dcs8/6-3P 15
IVcJ1, subtype 3-specific ORFs; J3, dcs and Tn400181/108 16
IVcJ1, subtype 3-specific ORFs; J3, dcs2314AY271717
IVAJ1, subtype 3-specific ORFs; J3, dcs and pUB110cm11EU437549
IVEJ1, subtype 3-specific ORFs; J3, subtype 2-specific ORFsAR43/3330.1 20
IVdJ1, subtype 4-specific ORFs; J3, dcsJCSC4469 16
IVgJ1, subtype 5-specific ORFs; J3, dcsM03-68 14
IVhJ1, subtype 6-specific ORFs; J3, dcsEMRSA-15 17
IViJ1, subtype 7-specific ORFs; J3, dcsJCSC6668 2
IVjJ1, subtype 8-specific ORFs; J3, dcsJCSC6670 2
IV (2B&5)IV variantJ1, subtype 3-specific ORFs; J3, SCC carrying ccrCZH47 6
V (5C2)VJ1, subtype 1-specific ORFs; J2, subtype 1-specific ORFs; J3, subtype 1-specific ORFsWIS(WBG8318) 10
V (5C2&5)VT, VIIJ1, subtype 2-specific ORFs; J2, sutype 2-specific ORFs; J3, SCC carrying ccrCTSGH17, PM1 3, 22
VI (4B)VIJ1, subtype 1-specific ORFs; J3, dcsHDE288 19
VII (5C1)5C1J1, subtype 1-specific ORFs; J2, subtype 1-specific ORFs; J3, subtype 1-specific ORFsJCSC6082 1
VIII (4A)VIIIJ1, subtype 1-specific ORFs; J2, subtype 1-specific ORFs; J3, subtype 1-specific ORFsC10682, BK20781 23; FJ670542
  • a SCCmec elements that satisfy the following criteria are listed as follows: entire regions of SCCmec elements have been sequenced, or the essential parts of the mec gene complex and the ccr gene complex have been fully sequenced.

  • b The first categories for classifying SCCmec elements. The combinations of the ccr gene complex and the mec gene complex carried by the elements are indicated in parentheses.

  • c The names reported in original literature are listed. Assigned numbers or names that specify these elements would be given by IWG-SCC and would be seen at the website (http://www.SCCmec.org [under construction]).

  • d Key loci are indicated in parentheses. pls, plasmin-sensitive surface protein; dcs, downstream constant segment; kdp, potassium-dependent ATPase operon.

  • e GenBank/EMBL/DDBJ accession numbers are indicated in cases of direct submission.