TABLE 1.

Susceptibilities of wild types and E. coli J53 transconjugants to β-lactam and quinolone antibiotics

StrainaMIC (μg/ml)bqnrB alleleβ-Lactamase
NACIPLEVOMOXIFOXCTXCAZ
E. coli J53 Azir80.030.060.064<0.251
12-1183>64>16>16>8>12816128 B4 DHA-1
T12-1183320.250.51324128
35>64164>832>128>128 B5 SHV-12
T35320.50.250.5416128
07-006>6416881664128 B2 SHV-12
T07-006320.50.251416128
03-222>6416168164128 B2 SHV-12
T03-2223210.250.54264
12-1502160.50.250.5>12864128 B2 CMY-1
T12-15023210.250.5>1286464
  • a T, an E. coli J53 Azir transconjugant of each isolate. Isolate 12-1502 was E. coli, and all other clinical isolates were K. pneumoniae.

  • b NA, nalidixic acid; CIP, ciprofloxacin; LEV, levofloxacin; MOX, moxifloxacin; FOX, cefoxitin; CTX, cefotaxime; CAZ, ceftazidime.