TABLE 2.

Representative S. aureus isolates: origins, antimicrobial MICs, and resistance genes

IsolateSite-dateaMIC (μg/ml)bResistance gene(s)cermB-aadE-sat4-aphA-3 gene cluster
VANOXAERYCLITETDOXLEVGENvantetermAminoglycosides
VRSA 595Urine-3/2464>16>8>8>1641632vanAtet(S), tet(U)erm(B), msrAaac(6′)-aph(2"), aadE, aph(3")-IIIa+
MRSA 5737G. tube sited-4/21>16>8≤0.12≤0.50.516>64msrAaac(6′)-aph(2"), ant(4′)-Ia, aph(3")-IIIa
MRSA 5739Rectum-4/21>16>8≤0.12≤0.5≤0.2516>64msrAaac(6′)-aph(2"), ant(4′)-Ia, aph(3")-IIIa
MRSA 2513Biofilm-4/151>16>8>8≤0.5≤0.2516≤4erm(B), msrAaadE, aph(3")-IIIa+
MRSA 2530Biofilm-4/151>16>8≤0.12≤0.5≤0.2516≤4msrAaph(3")-IIIa
VRSA 2514Biofilm-4/1532>16>8>8>1641664vanAtet(S), tet(U)erm(B), erm(C), msrAaac(6′)-aph(2"), aadE, aph(3")-IIIa+
MRSA 5735Urine-4/202f>16>8>8841616vanAtet(S), tet(U)erm(B), msrAaac(6′)-aph(2"), aadE, aph(3")-IIIa+
MRSA 5736Urine-4/204f>16>8>88416>64vanAtet(S), tet(U)erm(B), msrAaac(6′)-aph(2"), aadE, aph(3")-IIIa+
MRSA 5733Urine-4/20 (cath.)e4f>16>8>88416>64vanAtet(S), tet(U)erm(B), msrAaac(6′)-aph(2"), aadE, aph(3")-IIIa+
VRSA 5734Urine-4/20>128>16>8>816816>64vanAtet(S), tet(U)erm(B), msrAaac(6′)-aph(2"), aadE, aph(3")-IIIa+
  • a Date is shown as month/day.

  • b CLI, clindamycin; DOX, doxycycline; ERY, erythromycin; GEN, gentamicin; LEV, levofloxacin; OXA, oxacillin; TET, tetracycline; VAN, vancomycin.

  • c —, gene not detected by PCR.

  • d G. tube site, gastrostomy tube site.

  • e cath., catheterized urine specimen.

  • f Indicates isolates with a vancomycin-susceptible or -intermediate phenotype but that were vanA+ by PCR.