TABLE 1.

Comparison of E. coli counts in serum or anticoagulated blood between rAAV2-BPI23-Fcγ1 and rAAV2-EGFP gene-transferred mice

Mouse injectionaBacterial count (CFU)
Expt 1Expt 2Expt 3Mean± SD
Serum
    rAAV2-BPI23-Fcγ122231921.33 ± 2.08
    rAAV2-EGFP31303933.33 ± 4.93
Anticoagulated blood
    rAAV2-BPI23-Fcγ117131113.67 ± 3.06
    rAAV2-EGFP32314134.67 ± 5.51
  • a Sera or anticoagulated blood samples were collected from the gene-transferred mice 2 weeks after injection. Serum from rAAV2-BPI23-Fcγ1 gene-transferred mice contains secreted BPI23-Fcγ1 protein with no phagocytes. Serum from rAAV2-EGFP gene-transferred mice does not contain BPI23-Fcγ1 protein and phagocytes. Anticoagulated blood of rAAV2-BPI23-Fcγ1 gene-transferred mice contains secreted BPI23-Fcγ1 protein and phagocytes. Anticoagulated blood of rAAV2-EGFP gene-transferred mice contains only phagocytes, with no BPI23-Fcγ1 protein.