TABLE 1.

Demographic characteristics and outcomes of the studied 101 adult patients with LRTI

CharacteristicNo. (%), unless otherwise specified
Gender
    Male63 (62%)
    Female38 (38%)
Race
    Black6 (6%)
    Caucasian80 (79%)
    Hispanic3 (3%)
    Other12 (12%)
Age, yr [median (range)]67 (29-98)
Body weight, kg [median (range)]70.2 (42.7-105)
Creatinine clearance, ml/min [median (range)]65.3 (14-150)
Serum creatinine, mg/dl [median (range)]1.1 (0.5-6.7)
Infection type
    Pneumonia89 (88.1%)
    Bronchitis11 (10.9%)
    Other LRTI1 (0.99%)
Common pathogensa
    Streptococcus pneumoniae27 (26.7%)
    Staphylococcus aureus14 (13.9%)
    Haemophilus influenzae11 (10.9%)
    Klebsiella pneumoniae9 (8.9%)
    Escherichia coli8 (7.9%)
    Pseudomonas aeruginosa7 (6.9%)
Clinical success89 (88.1%)
Microbiological successb82 (86.3%)
  • a Most common bacteria isolated; defined according to the pathogen with the highest meropenem MIC.

  • b Ninety-five of the 101 patients were microbiologically evaluable.