TABLE 1.

Univariate analysis of risk factors for digestive tract CR-PA colonization of ICU patients

CharacteristicPatients CR-PA colonized (n = 30)Patients not CR-PA colonized (n = 224)P value
Mean age (yr) ± SD59.8 ± 15.057.1 ± 15.70.3
No. (%) of males/females18 (60)/12 (40)145 (65)/79 (35)0.6
No. (%) with immunosuppression3 (10)36 (16)0.5
No. (%) with neutropenia1 (3)7 (3)1.0
No. (%) with malignancy or AIDS2 (7)31 (14)0.3
No. (%) tested in 200317 (57)102 (45.5)
No. (%) tested in 200413 (43)122 (54.5)0.2
No. (%) with prior CS-PA15 (50)75 (33)0.01
No. (%) with antibiotic exposure28 (93)143 (64)<0.01
No. (%) with carbapenem exposure19 (63)45 (20)<0.01
No. (%) with fluoroquinolone exposure7 (23)15 (7)0.01
No. (%) with vancomycin exposure4 (13)27 (12)0.7
No. (%) with cephalosporin exposure1 (3)16 (7)0.7
No. (%) with amikacin exposure8 (27)32 (14)0.1
No. (%) with piperacillin-tazobactam exposure3 (10)17 (7.5)0.7
No. (%) with previous surgery13 (43)59 (26)0.05
No. (%) with mechanical ventilation26 (87)139 (62)<0.01
No. (%) with a urinary catheter27 (90)194 (87)0.7
No. (%) with a venous catheter28 (93)188 (84)0.06
No. (%) with total parenteral nutrition13 (39)33 (15)<0.001
Mean SAPSa ± SD40.6 ± 10.428.0 ± 14.8<0.001
Mean ICU stay (days) ± SD16.3 ± 9.08.6 ± 8.0<0.001
  • a SAPS at time of ICU admission.