TABLE 3.

MICs of various compounds against S. aureus rplC mutants

Alteration(s) in L3MIC (μg/ml) ofa:
REPTIACMTCLEVMUP
None (wild type)≤0.060.2540.250.50.06
D159Y0.25440.250.50.06
G155R0.5480.250.50.06
S158L0.25240.250.50.06
G152D0.25480.250.50.06
G152D D159Y11680.250.250.06
G152D G155R11680.250.250.06
G152D D159Y G144R43280.250.250.06
G152D D159Y G155R4>6440.250.250.06
G152D D159Y G155R H134N0.125280.250.50.06
G152D D159Y G155R A150T0.25480.250.1250.06
  • a Abreviations: REP, retapamulin; TIA, tiamulin; CM, chloramphenicol; TC, tetracycline; LEV, levofloxacin; MUP, mupirocin.