TABLE 3.

Percentages of mortality documented for mice on the different antibiotic regimens after their lungs were infected with the PAO1 or PAOΔmutS P. aeruginosa straina

Therapeutic group (no. of mice)Mortality (%)
PAO1PAOΔmutS
CIP (30)26.726.7
TOB (30)66.760.0
CAZ (30)56.743.3
CIP-TOB (30)13.316.7
CAZ-TOB (30)40.030.0
CAZ-CIP (30)40.036.7
Placebo (60)60.058.3
  • a Results for CIP, TOB, and CIP-TOB were obtained in a previous study (23) and are included for comparison.