TABLE 2.

Weight loss in mice infected with influenza virus (A/Japan/305/57) given 60 mg/kg gemfibrozil once daily from days 4 to 10 after virus exposure

Gemfibrozil dose (mg/kg/day)No. of mice that survived/totalMedian survival time (days)95% confidence interval (days)Avg % day 0 body wt ± SD on indicated day p.i. (no. of mice remaining on that day)
681012
013/5087-1076.1 ± 4.2 (47)70.3 ± 3.8 (29)68.3 ± 8.7 (19)70.8 ± 13.0 (16)b
6024/46NAa10+76.7 ± 5.2 (45)71.1 ± 7.1 (36)71.7 ± 11.1 (30)77.0 ± 13.4 (25)c
  • a NA, median survival time cannot be reported, as more than half the mice survived the experiment.

  • b After day 12 there were three more deaths, two on day 13 and one on day 17.

  • c After day 12 there was one more death, on day 13.