TABLE 1.

Antimicrobial susceptibility patterns of carbapenem-resistant K. pneumoniae strains 469 and 490 and their respective transformants

Antimicrobial agent or enzymeMIC (μg/ml)
K. pneumoniae 469Transformant 469K. pneumoniae 490Transformant 490E. coli GeneHogs
Ampicillin/sulbactam>32>32>32>32<4
Ceftriaxone>64>64>648<1
Ceftazidime>64>64>6416<1
Cefepime>6432>644<1
Aztreonam>6432>64>64<1
Piperacillin>128>128>128>128<4
Piperacillin/tazobactam>128>128>12864<4
Ciprofloxacin<0.25<0.25>4<0.25<0.25
Amikacin416>64<2<2
Gentamycin>16>162<1<1
Colistin0.250.0640.250.0640.064
Imipenem164324<0.25
Meropenem84322<0.25
Ertapenem164642<0.25
Tigecycline20.520.50.016
bla enzymes detectedKPC-2 OXA-4, CTX-M-10KPC-2 OXA-4, CTX-M-10KPC-3 TEM-1KPC-3 TEM-1None