TABLE 4.

Antimicrobial susceptibilities of H. influenzae isolates to other antibiotics according to PCR-based genotypes

Antimicrobial agentPCR-based genotypeNo. of isolatesMIC (μg/ml)Susceptibility (%)a
MIC50MIC90RangeSIR
Clavulanate-amoxicillingBLNAS870.510.25-210000
Group I/II gBLNAR98140.25-1692.9NA7.1
Group III gBLNAR748322-3226.7NA73.3
Total2591160.25-32
CefpodoximegBLNAS870.120.12≤0.06-0.12100NA0
Group I/II gBLNAR980.252≤0.06-890.8NA9.2
Group III gBLNAR74816≤0.06-649.1NA91.9
Total2590.258≤0.06-64
CefditorengBLNAS87≤0.06≤0.06≤0.06-0.12NANANA
Group I/II gBLNAR98≤0.060.12≤0.06-0.5NANANA
Group III gBLNAR740.250.5≤0.06-8NANANA
Total259≤0.060.5≤0.06-8
CefuroximegBLNAS87120.25-1697.71.11.2
Group I/II gBLNAR982160.25-6466.312.321.4
Group III gBLNAR74641280.25->1281.44.194.6
Total25921280.12->128
ClarithromycingBLNAS878162-3279.317.23.5
Group I/II gBLNAR988162-3275.522.52.0
Group III gBLNAR748164-1660.839.20
Total2598162-32
AzithromycingBLNAS87240.25-898.8NA1.2
Group I/II gBLNAR98240.5-1695.9NA4.1
Group III gBLNAR74240.5-897.3NA2.7
Total259240.25-16
TelithromycingBLNAS87240.5-897.72.30
Group I/II gBLNAR98240.5-893.96.10
Group III gBLNAR74241-887.812.20
Total259240.5-8
LevofloxacingBLNAS87≤0.06≤0.06≤0.0610000
Group I/II gBLNAR98≤0.06≤0.06≤0.06-0.1210000
Group III gBLNAR74≤0.06≤0.06≤0.06-0.510000
Total259≤0.06≤0.06≤0.06-0.5
MeropenemgBLNAS87≤0.06≤0.06≤0.06-0.1210000
Group I/II gBLNAR980.120.25≤0.06-0.510000
Group III gBLNAR740.250.5≤0.06-290.509.5
Total2590.120.5≤0.06-2
  • a S, susceptible; I, intermediate; R, resistant; NA, not available.