TABLE 3

Distribution of therapeutic drug monitorings as a function of measured creatinine clearance intervals

Antibiotic(s)aNo. (%) of TDMs at CLCR of:b
120–180 ml/min181–240 ml/min241–300 ml/min>300 ml/min
All130 (51)67 (26)24 (9)35 (14)
FEP7 (32)2 (9)2 (9)0 (0)
CAZ7 (32)2 (9)0 (0)2 (9)
PIP43 (48)22 (25)11 (12)13 (15)
MEM73 (50)41 (28)11 (8)20 (14)
  • a FEP, cefepime; CAZ, ceftazidime; PIP, piperacillin; MEM, meropenem.

  • b Creatinine clearance (CLCR) obtained from 24-h urine collections. TDMs, therapeutic drug monitorings.