TABLE 1

Telavancin MIC90 of CPT for 333 S. aureus strains from CF patientsa

StrainMIC (μg/ml)b
CPTTLVDAPVANLZD
MSSA (n = 180)0.5 (100)0.06 (100)0.25 (100)1.0 (100)1–2 (99.4)
MRSA (n = 153)
    CPTs (n = 130)<1.5 (85)
    CPTir (n = 20)1.5–2 (13)0.06 (100)0.5–1 (100)1–1.5 (100)1–2 (98.1)
    CPThr (n = 3)>32 (2)
  • a The MIC90 of CPT was determined by the microdilution method in Mueller-Hinton broth supplemented with polysorbate 80 (0.002%) and was compared to the MIC90s of the DAP, VAN, LZD, and CPT agents following CLSI guidelines.

  • b Values in parentheses represent the percentage of isolates with the indicated MIC.