TABLE 3

Estimated change of Shannon index and unweighted UniFrac distances between D0 and D3 needed to decrease the mortality rate to various levels in the hamster model of moxifloxacin-induced Clostridium difficile infection

Mortality rate (%)Change of Shannon index (95% CI)Unweighted UniFrac distance (95% CI)
10−1.0 (−1.2, −0.8)0.58 (0.55, 0.60)
5−0.7 (−1.1, −0.4)0.55 (0.53, 0.58)
1−0.2 (−0.7, 0.3)0.51 (0.47, 0.55)