Clinical characteristics and outcomes of patients infected with carbapenem-resistant Enterobacteriaceae

Infection typesb
    Bacteremia51/664 (7.7)
    Intra-abdominal infection51/664 (7.7)
    Lower respiratory tract infection434/664 (65.4)
    Meningitis10/664 (1.5)
    Urinary tract infection110/664 (16.6)
    Wound infectionc9/664 (1.4)
    Other infectionsd12/664 (1.8)
APACHE II score (median [IQR])e17 (12–23)
Septic shock58/664 (8.7)
Laboratory findings
    White blood cells/mm3
        Median (IQR)10,000 (5,925–14,165)
            <4,00026/567 (4.6)
            >10,000332/567 (58.6)
    C-reactive protein >10 mg/liter252/320 (78.8)
        0.5 to 2 ng/ml73/312 (23.4)
        >2 ng/ml93/312 (29.8)
Clinical outcomes
    Length of stay (median [IQR]) (days)29 (16–48)
    ICU admission378/664 (56.9)
    Length of ICU stay (median [IQR]) (days)5 (0–15)
    Discharge disposition
        Home363/662 (54.8)
        Long-term acute facility7/662 (1.1)
        Follow-up outpatient41/662 (6.2)
        Transfer to other hospitals29/662 (4.4)
    In-hospital mortality222/662 (33.5)
    Bacteremia-associated mortality22/51 (43.1)
    Intra-abdominal infection-associated mortality13/50 (26)
    Lower respiratory tract infection-associated mortality148/425 (34.8)
    Urinary tract infection-associated mortality30/99 (30.3)
  • a Data are presented as the number/total number (%), unless otherwise indicated.

  • b Patients with multiple diagnoses were listed under more than one category, so total numbers may be larger than the number of patients.

  • c Wound infection includes wound infection and surgical site infection.

  • d Other infections include skin and soft tissue infection and other infections.

  • e APACHE II, Acute Physiology and Chronic Health Evaluation II.