TABLE 2

Demographic characteristics of patients infected with carbapenem-resistant Enterobacteriaceae

CharacteristicaDatab
Female214/664 (32.2)
Age (median [IQR]) (yr)62 (45–74)
    0–457/664 (8.6)
    5–1713/664 (2.0)
    18–49131/664 (19.7)
    50–64159/664 (23.9)
    65–79192/664 (28.9)
    ≥80112/664 (16.9)
Travel history to Southeast Asia5/656 (0.8)
Health care exposure during prior yr
    Acute care hospitalization246/663 (37.1)
    Dialysis44/661 (6.7)
    Long-term acute care facility47/663 (7.1)
    Resident of a long-term-care facility74/663 (11.2)
Underlying conditions
    Charlson comorbidity index (median [IQR])1 (0–3)
    None107/661 (16.2)
    Cancerc106/661 (16.0)
    Diabetes mellitus140/664 (21.1)
    Heart diseasesd167/664 (25.2)
    Hypertension281/664 (42.3)
    Immunodeficiencye44/663 (6.6)
    ICU stay137/660 (20.8)
    Liver diseasesf60/663 (9.0)
    Neurological diseasesg194/662 (29.3)
    Pulmonary diseasesh237/662 (35.8)
    Renal diseasesi98/662 (14.8)
    Receipt of corticosteroids99/660 (15)
    Receipt of immunosuppressor8/661 (1.2)
    Smoking history110/664 (16.6)
Indwelling devices prior to culture
    Arterial cannula38/663 (5.7)
    Central venous catheter265/661 (40.1)
    Gastric tube195/660 (29.5)
    Tracheal cannula260/663 (39.2)
    Tracheotomy161/662 (24.3)
    Urinary catheter428/661 (64.8)
Antimicrobial use prior to culture within 30 days
    None60/660 (9.1)
    Single antimicrobial use237/592 (40.0)
    Multiple antimicrobial use355/592 (60.0)
    Third- or fourth-generation cephalosporin use214/592 (36.1)
    Carbapenem use191/592 (32.3)
  • a IQR, interquartile range; ICU, intensive care unit.

  • b Data are presented as the number/total number (%), unless otherwise indicated.

  • c Cancer includes malignancy in lung, digestive tract, gynecology, hematological system, and neurological system.

  • d Heart diseases include congestive heart failure, coronary heart disease, valve replacement, and congenital heart disease.

  • e Immunodeficiency includes splenectomy, agranulocytosis, and chemotherapy.

  • f Liver diseases include cirrhosis, hepatitis, liver abscess, hepar adiposum, and hepatic injury.

  • g Neurological diseases include stroke, transient ischemic attack, cerebral palsy, and meningitis.

  • h Pulmonary diseases include chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease, history of pneumonia and tuberculosis, emphysema, respiratory failure, and infection.

  • i Renal diseases include azotemia and chronic kidney disease.