TABLE 2

Physicochemical parameters and Lipinski's rule of fivea

CompoundWater solubility (mg/liter)No. of donorsNo. of acceptorsLogPMW
DB21042.394245.154324.383
DB21311.041245.293342.373
DB21611.416345.215330.412
DB21712.775245.030316.404
DB21863.887244.529317.392
DB2187−5.9124.9333.419
DB21911.416345.215330.412
DB21925.356244.305315.376
DB22120.934245.309345.446
DB22172.587244.695329.403
Bz376.248150.11260.253
  • a MW, molecular weight; LogP, partition coefficient.