TABLE 2

Effects of PABA on the FIC indices of the sulfa drug-fluconazole combinations

Sulfa drug-fluconazole combinationFIC index under PABA concn (μg/ml) of:
0148163264128
4-Amino phenyl sulfone (dapsone)0.06250.1250.250.50.522>2
Sulfadiazine0.06250.1250.50.50.5>2>2>2
Sulfamethazine0.1250.51122>2>2
Sulfamethoxazole0.03120.03120.06250.06250.1250.2522
Sulfadoxine0.1250.1250.250.250.522>2
Sulfamerazine0.1250.1250.250.250.52>2>2
Sulfamonomethoxine0.03120.06250.1250.1250.1250.250.50.5
Sulfadimethoxine0.06250.1250.250.250.25>2>2>2
Sulfathiazole0.1250.250.50.50.52>2>2
Sulfapyridine0.250.522222>2
Sulfametopyrazine (sulfalene)0.06250.06250.1250.1250.1250.50.52
Sulfametoxydiazine (sulfameter)0.1250.1250.250.250.52>2>2
Sulfisomidine0.1250.5222>2>2>2
Sulfisoxazole (sulfafurazole)0.1250.250.250.50.52>2>2
Sulfamethoxypyridazine0.06250.1250.250.250.52>2>2