*C*_{max} (μg/ml) | | | | |

LS geometric mean | 21.6 | 23.2 | 22.8 | 24.1 |

LS geometric mean (90% CI) | 19.1, 24.3 | 20.6, 26.1 | 17.5, 29.6 | 18.5, 31.4 |

LS geometric mean ratio | 1.07 | | 1.06 | |

LS geometric mean ratio (90% CI) | 1.01, 1.14 | | 1.01, 1.11 | |

AUC_{0–}_{t} (μg · h/ml) | | | | |

LS geometric mean | 65.5 | 71.2 | 73.6 | 78.8 |

LS geometric mean (90% CI) | 58.1, 73.4 | 63.2, 80.2 | 56.5, 95.9 | 60.5, 103 |

LS geometric mean ratio | 1.09 | | 1.07 | |

LS geometric mean ratio (90% CI) | 1.04, 1.13 | | 1.04, 1.11 | |

AUC_{0–inf} (μg · h/ml) | | | | |

LS geometric mean | 66.0 | 71.9 | 74.6 | 79.9 |

LS geometric mean (90% CI) | 58.6, 74.4 | 63.8, 81.1 | 57.4, 96.9 | 61.5, 104 |

LS geometric mean ratio | 1.09 | | 1.07 | |

LS geometric mean ratio (90% CI) | 1.05, 1.14 | | 1.04, 1.11 | |