TABLE 3

Multivariate analysis of factors independently associated with Gram-negative IE

FactoraUnivariate analysisMultivariate analysis
OR95.0% CIPOR95.0% CIP
LowerUpperLowerUpper
Genitourinary tract10.673.9328.92<0.00113.604.6339.93<0.001
Immunosuppression4.381.5512.370.0035.161.616.620.006
CIED2.851.336.060.0053.601.558.200.003
New regurgitation0.370.170.770.0070.390.170.900.027
Device-related endocarditis3.321.199.300.017
CVC2.561.135.800.021
Heart failure0.480.250.940.003
  • a CIED, cardiac implantable electronic device; CVC: central venous catheter (including any of the following: arteriovenous fistula, chronic intravenous catheter, or acute central catheter).